Search Results for: label/development
Towards better drug development, fewer side effects?
…thinks she’s counting CD4 T cells, she may actually be counting some macrophages. That overlap leads to all sorts of experimental optimization issues. An exceptionally talented flow cytometrist can assemble panels of perhaps 12 or so dyes, but it might take months to get everything just right. That’s where the mass cytometry comes in. Commercialized by DVS Sciences, mass cytometry is essentially the love-chid of flow cytometry and mass sp…
Authored by Jeffrey Perkel on September 24, 2012
Elephant mimics Korean, delighting Arrested Development fans
An Asian elephant snacks on watermelon.Photo via Wikimedia Commons.Photo credit: Fir0002/Flagstaffotos Arrested Development fans who like elephants, this is your story. An elephant named Koshik can mimic about seven words of Korean, and one of those words is “annyong,” or “hello.” It’s not unheard of for elephants to mimic sounds, but Koshik, who makes his Korean sounds by putting his trunk in his mouth, is…
Authored by Emily Willingham on November 2, 2012
He found out he has ovaries*
…port about the man was published in the Hong Kong Medical Journal, which you can read in its entirety here [PDF]. The man, who was born in Vietnam, had a history of medical issues, including having stopped growing when he was 10, which resulted in his being just under 4 feet, 6 inches (1.37 m) tall. He was an orphan who, according to the case study, had a “micropenis” (just what it sounds like) and a condition called hypospadias, in w…
Authored by Emily Willingham on June 6, 2013
Biology Explainer: The big 4 building blocks of life–carbohydrates, fats, proteins, and nucleic acids
…e X Extra: A triglyceride can have up to three different fatty acids attached to it. Canola oil, for example, consists primarily of oleic acid, linoleic acid, and linolenic acid, all of which are unsaturated fatty acids with 18 carbons in their chains. Why do we take in fat anyway? Fat is a necessary nutrient for everything from our nervous systems to our circulatory health. It also, under appropriate conditions, is an excellent way to store up…
Authored by Emily Willingham on June 8, 2012
What is a beating embryonic heart?
It’s pretty much the same in any vertebrate. by Emily Willingham The governor of North Dakota recently signed a law making abortions illegal if a heartbeat is detectable in the embryo. Perhaps the emphasis on this beating organ isn’t a surprise. The heart carries strong emotional connotations, hence its use in anti-abortion campaigns. It connotes love. It symbolizes compassion, as in “have a heart.” It symbolizes heal…
Authored by Emily Willingham on April 3, 2013
Creating viruses to create the vaccines?
…world had to wait several months for the right virus to be isolated for use in a vaccine. In March, the U.S. Centers for Disease Control and Prevention published a report indicating that H1N1 vaccination prevented 700,000 to 1,500,000 cases. But the report authors note that more illnesses and deaths could have been prevented if the vaccine had been available earlier. In spite of being a public health threat, the influenza virus holds a major adv…
Authored by DXS Contributor on May 20, 2013
Xplainer: How do you date a pregnancy?
…and 22. Pregnancy is often detected after the first missed period. This graphic is intentionally simple, removing all the hormones and other fun stuff (Ed: which you can find here). You’ll note that it says approximately day 14 and day 28. In textbooks, we often see that women have 28-day cycles and everything has a nice schedule. However, women are not textbooks and sometimes have shorter or longer cycles and/or have ovulation at slightly diffe…
Authored by Emily Willingham on October 3, 2012
Old ovaries, new eggs? Hatching a debate
…adling puts it: “You have a much better chance of actually helping someone with infertility if you know what the real biology is. Right now, we’re a ways from really understanding the full biology, but we’re making progress.” 1 Direct quote from the third edition of “Human Physiology: An Integrated Approach”, one published by Pearson Education in 2004 and used in medical school classes. [Image credit: front page and thumbnail oocyte image, publi…
Authored by DXS Contributor on May 15, 2013
The Bright Crystal
…he molecular structures of drug targets to design molecules that “fit” them like a lock to a key. The technique most often used to solve those molecular structures is x-ray crystallography. With this approach, which turned 100 years old in November, a high-powered beam of x-rays is shot at a crystal of protein molecules. The x-rays collide with the crystal’s atoms, scattering at specific angles. Working backwards from that information, researc…
Authored by Jeffrey Perkel on December 5, 2012
The path from science to alarmism: How science gets twisted before it gets to you
…ajority of what they’re looking at has never been demonstrated to have any kind of relationship to autism, not even a correlation. Problem #1 is the unnecessary autism name-checking. Problem #2 is much worse, it’s the list of 10 chemicals they suggest for future study. The list itself isn’t a bad idea, I guess. They’re suggesting places for potential research, which certainly needs to be done. But it does reek a little bit of the kind of thing ma…
Authored by Emily Willingham on May 4, 2012