Search Results for: label/sandwich ELISA

  • Pregnancy 101: The science behind the wand of destiny

    …om laughing so hard, let us get back to the science. The first “slice of bread” is called the reaction zone, the “sandwich filling” is called the test zone, and the “last slice of bread” is called the control zone (see figure 2). Each of these zones is coated with capture antibodies, but differ from each other in how they work.  The antibodies on the reaction zone will capture only hCG and will detach from the strip upon exposure to urine. The…

    Authored by on November 26, 2011

  • Biology Explainer: The big 4 building blocks of life–carbohydrates, fats, proteins, and nucleic acids

    …molecules themselves break down into a surprisingly small number of building blocks. The proteins that make up all of the living things on this planet and ensure their appropriate structure and smooth function consist of only 20 different kinds of building blocks. Nucleic acids, specifically DNA, are even more basic: only four different kinds of molecules provide the materials to build the countless different genetic codes that translate into all…

    Authored by on June 8, 2012

  • After Newtown missteps, journalists get guidelines

    …almost twice as likely to say that they don’t want to live or work near a person with mental illness if they read an article about a person with mental illness involved in a mass shooting, according to a study published March 20 in the American Journal of Psychiatry. Interestingly, this tendency is the same even if the article avoids any mention of mental illness. This may be because this link between violence and mental illness is deeply engrain…

    Authored by on March 27, 2013

  • How pregnant are you? Let’s find out

    …or “slipping” the top plate), they flow bottom-to-top. Samples and reagents are loaded in one configuration, and the chip is “slipped” to start the readout process. The SlipChip design Source: Nat. Commun. 3:1283 doi: 10.1038/ncomms2292 (2012). Here’s how the authors describe it: In the SlipChip, two pieces of glass etched with microfluidic wells and channels are assembled together in the presence of mineral oil. A fluidic path is for…

    Authored by on January 6, 2013

  • Shmeat and Potatoes: The dinner of the future?

    …t on this petri dish to kitchen dish phenomenon. The shmeaty deets When it comes to producing shmeat, scientists are taking advantage the extensive cell culture technologies that have been developed over the course of the 20th century (for a brief history of these developments, check this out).  Because of what we have learned, we can easily determine the conditions under which cells grow best, and swiftly turn a few cells into a few million…

    Authored by on July 20, 2012

  • Unicorns and Brainbows

    Brainbow is a mouse with a rainbow brain. By Jeffrey Perkel    A couple weeks ago I wrote about the beautiful world right under our noses, a world visible only under the microscope. The cover image for that post was this picture, a “‘Brainbow’ transgenic mouse hippocampus,” which placed 18th in the 2008 Nikon Small World Photomicroscopy contest. Brainbow technology also won the 2007 Olympus Bioscapes contest, with this be…

    Authored by on May 6, 2013

  • Is the bar high enough for screening breast ultrasounds for breast cancer?

    …n controversial. What’s new is the “Are You Dense?” patient movement and legislation to inform women that they have dense breasts. Merits and pitfalls of device approval The approval of breast ultrasound hinges on a study of 200 women with dense breast evaluated retrospectively at 13 sites across the United States with mammography and ultrasound. The study showed a statistically significant increase in breast cancer detection when ultrasound was…

    Authored by on September 21, 2012

  • Autism and the DSM-5

    …ial social aspect of this change, and the one thing that might, when it comes to autism, elevate the DSM-5 above the level of doorstop. [Image credit: Dave Bullock, UK, via Wikimedia Commons under Creative Commons Attribution 2.0 generic license.]…

    Authored by on April 23, 2013

  • Depressing genes

    Can depression be a matter of genetic fate? by Siobhan Mitchell          [This post is the latest installment in our I Am Mental Illness series.] What if you could know if you were fated to be depressed? With the rise of personal genotyping services such as 23andme, almost can find out what their psychiatric ‘fate’ will be, but what do you do with this information once you have it? When I first considered testing myself for depressio…

    Authored by on May 17, 2013

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