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Search Results for: label/x-ray crystallography

  • The Bright Crystal

    …hen be assembled to recreate the initial molecular structure. In this case, the team collected some 4 million snapshots, 293,195 of which included a diffraction pattern. They combined 61% of those (178,875) to produce a final 3D structure at near atomic resolution. By combining thousands of individual diffraction images (top), you can solve a structure. Shown at bottom is the 2.1-angstrom structure of trypanosomal cathepsin-B (Source) …

    Authored by on December 5, 2012

  • Crystallographers of merit

    …B.A. with honors from Somerville College at Oxford University in 1931, then went onto a research fellowship there. She earned her D.Phil. from Cambridge University in 1936, followed by marrying Thomas Hodgkin in 1937. She had 3 children within the next 10 years. Dr. Hodgkin did research using x-ray crystallography to study and clarify large biomolecules and pioneered the use of computers in crystallography. In 1964, she received the Nobel Prize i…

    Authored by on March 7, 2013

  • The Women in ‘Modern Men of Science’

    . Meitner, whom we’ve written about before at Double X Science, received her doctorate in physics at the University of Vienna in 1906. She began work at the University of Berlin, studying with Max Planck and beginning a 30-year collaboration with Otto Hahn. Dr. Meitner is known at “the mother of the atomic bomb,” although her true discovery is the physical theory of nuclear fission, built upon many experiments and published in 1939. Unfortu…

    Authored by on April 11, 2013

  • Biology Explainer: The big 4 building blocks of life–carbohydrates, fats, proteins, and nucleic acids

    …ll selection of different materials: bricks, mortar, iron, glass, and wood. Arranged in different ways, these few materials can yield a huge variety of structures. We encountered functional groups and the SPHONC in Chapter 3. These components form the four categories of molecules of life. These Big Four biological molecules are carbohydrates, lipids, proteins, and nucleic acids. They can have many roles, from giving an organism structure to be…

    Authored by on June 8, 2012

  • Double X Science panel at GeekGirlCon 2012

    with a welcome and gratitude to the organizers and attendees and our tagline “Science, I am Just That Into You.” We were selected to appear with a lot of fantastic programming over the weekend. We introduced our 3 panelists: Adrienne Roehrich, your panel moderator and the chemistry editor at Double X Science Emily Willingham, founder and managing editor  Ray Burks, contributor to Double X Science  Photo by Ryan Roehrich and u…

    Authored by on August 14, 2012

  • After Newtown missteps, journalists get guidelines

    …almost twice as likely to say that they don’t want to live or work near a person with mental illness if they read an article about a person with mental illness involved in a mass shooting, according to a study published March 20 in the American Journal of Psychiatry. Interestingly, this tendency is the same even if the article avoids any mention of mental illness. This may be because this link between violence and mental illness is deeply engrain…

    Authored by on March 27, 2013

  • Why Can You Hear Around Corners But Not See?

    …ecific wavelength of sound depends on the temperature and humidity of the air, but if we assume dry room-temperature air, a low-pitched sound has a wavelength of about 17 meters and high-pitched sounds have wavelengths around 2 centimeters. That’s a big range, and not all those sounds will travel around corners. Shorter wavelengths are ultrasound, which are probably most familiar for tracking the health of fetuses: these sound waves can pen…

    Authored by on December 27, 2011

  • Autism and the DSM-5

    …ial social aspect of this change, and the one thing that might, when it comes to autism, elevate the DSM-5 above the level of doorstop. [Image credit: Dave Bullock, UK, via Wikimedia Commons under Creative Commons Attribution 2.0 generic license.]…

    Authored by on April 23, 2013

  • Unicorns and Brainbows

    orite, shown below: A cerebellar flocculus, a lobe in the cerebellum, from the original Brainbow paper (Source) Since its original description, researchers have used the Brainbow concept extensively — it has been cited 361 times, according to the Web of Science – and extended it into zebrafish and fruit flies, both species that researchers frequently use in experiments to trace gene expression and how animals develop. But though Lich…

    Authored by on May 6, 2013

  • Depressing genes

    ter all, that’s one of the reasons why scientists are trying to identify risk genes: to design better treatments for those disorders. [Image credit: DNA, public domain image from US govt. Image of Prozac, credit Tom Varco, CC 3.0 license.] [Siobhan Mitchell obtained a Neurobiology Ph.D. at the State University New York at Albany (SUNY Albany), followed by a post-doctoral fellowship at University of Washington, Seattle. She currently works at the…

    Authored by on May 17, 2013

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